How to use if condition in a function mentioning the area?

programming flash
1

Hi,

How can I use if condition in a function?

If my mouse cursor not in the following area:
between x:150 & x:250
between y:50 & 350

Then the following condition to be applied:

function areaOut(e:MouseEvent):void {

TweenLite.to(ButtonsPanel2_mc, 0,{alpha:0, x:463.8, y:-400});
}

What is the code, Please?