Please help Javascript AND OR

can someone tell me how to check 2 “OR” statements with 1 “AND” statement?
eg:

I am trying this -

if(((document.registrationform.rnationality.value != “Indian”)||(document.registrationform.rnationality.value != “INDIAN”)) && (document.registrationform.rpassportno.value == “”))
{
alert(" done ")
}

but this is not working.

Aditya