Setting up mail in PHP

Hi all,
I was searching for a solution in php. I settled up my mail in php but its not working and throwing up some errors like

Warning: main(Mail.php): failed to open stream: No such file or directory in F:\hshome\xentaqsy est.xentaqsys.com\stores\mailS end.php on line 26

Fatal error: main(): Failed opening required ‘Mail.php’ (include_path=’.;c:\php4\pear’) in F:\hshome\xentaqsy est.xentaqsys.com\stores\mailS end.php on line 26

I am not getting wats happening are really getting stuck up with this problem. Please help me asap.

Any suggestion and will be greatly appreciated…
Thanks in advance