Syncing lights with audio in an Exhibit

I got stuck with a project of creating an installation where separate lights (say 10 or so) need to turn on and off based on the current position in a repeating audio track. On top of that, based on where the light is pointing, the audio will be coming from speakers near that location.

Anyone have any experience with anything like this? I’m not really sure where to start; what kind of hardware to consider and how it would be controlled (via a separate computer I assume?).