Need some advice on user support that has small screens

I just spent days workin on a design on my res of 1280x 960. and I even made the page center, and thought it was kinda small on my screen , come to find out POOF it is MASSSIZE on 800 x 600 screenss… :frowning: in the starting design phase what could I have done to design it so Iit would look good on both resz screesns ???

Any tips to deal with this kinda desgin bug