Chaning homepage

Hey guys, i have a question…i seem to have some sort of spy ware, or something of the sorts on my computer, i have adaware 6, and i scan / delete stuff everyday, but i have a persisting problem.

I have myhome page set to kirupa :), anyways, as soon as i open IE, it doesn’t really load my home page, it goes straight to a random ad site…any one have any idea on how to make it stop?