Looking for advice on CMS and suggestions

Awhile ago I drew up what I wanted my site to be. Basically an all around site for everything about me. Blogs are one sided as they are journals. I want to share my picture collection, my favorite files, have a forum, have my blog, have a place to host my “projects”(webcomics, videos, etc), have a place for movies and some articles I’d like to write.

http://doomedtoreality.com/files/Website/sitemap.jpg

I’m familiar enough with drupal(ran it and setup a few times) to know it can do all this. I’m just wondering yours all opinion on having a site LIKE this and how well a CMS could handle this. I’ve been debating lately over which CMS could handle this best without being overly complicated or if I should just build it by hand(keep in mind I know little about dreamweaver so I’d have to use a WYSIWYG). I’d like to build it with Flash but know less about Flash.

My main problem is setting up section homepages where they look a bit different and not just have the entire site a ton of links to every other section. Ideally I’d want it looking SORT of http://weareall.doomedtoreality.com/drupal5/ (this is an early version of the site done in Firefox and no finished). I’m don’t like having a “normal” website, with side navigation, and white backgrounds, I like dropdown menus.

My other concern is for comics I’d make I’d want them to be able to be archived but like comic # like all those webcomic sites do.

My other problem is I’d hope in setting this system up it’d be simple to keep track of and not hard to find something to edit it.

Well, I’m basically wondering your opinions on having an all encompassing site like this where as I could run a lot of this stuff on separate domains specialized to its thing. Like the webcomic, I’d want that to stand out, and it could have its own domain, but how would I make it stand out as a “speciality” to that site?

Just still mashing over this stuff in my head.

Hopefully the image works, or just “view image” or something.