Critique me - this is something different for me

I recently registered the domain to be my business site so can be my personal/community/e/n site.

For, I’m still developing the theme and I think I’m going for an understated, calm sort of medical/science journal theme, rather than the normal “I’m the most mega l33t php cgi xml adobe hax0r pimp on the planet” theme that you see all too often.

Here is a theme development study. Its a very different direction for me and I always have trouble judging my own work. What do you all think?